{"id":1266,"date":"2012-05-15T14:34:10","date_gmt":"2012-05-15T19:34:10","guid":{"rendered":"http:\/\/www.kateva.org\/sh\/?p=1266"},"modified":"2012-05-15T14:34:10","modified_gmt":"2012-05-15T19:34:10","slug":"crenezumab-to-prevent-alzheimers-the-columbia-study","status":"publish","type":"post","link":"http:\/\/www.kateva.org\/sh\/?p=1266","title":{"rendered":"Crenezumab to prevent Alzheimer&#8217;s: The Columbia study."},"content":{"rendered":"<p><a href=\"http:\/\/www.nytimes.com\/2012\/05\/16\/health\/research\/prevention-is-goal-of-alzheimers-drug-trial.html?_r=1&#038;pagewanted=2\">Link.<\/a> Done with great care. &#8220;&#8230; 100 family members who carry the mutation will receive the drug every two weeks&#8230; Another 100 mutation carriers will receive a placebo. And because many people do not want to know if they have the mutation, researchers will also include 100 non-carriers in the study; they will receive a placebo.&#8221;<\/p>\n<p>It is unlikely to work. We hope it will cause no harm. Even if it fails it will guide treatments for at least the youngest of this afflicted clan.<\/p>\n<p>Note that it will probably be 5+ years before we get results. That&#8217;s a clue as to how far we are from having good Alzheimer&#8217;s prevention. We should have  treated Alzheimer&#8217;s as an emergency 30 years ago, but of course 30 years from now people will say the same about our attitude to climate change.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Link. Done with great care. &#8220;&#8230; 100 family members who carry the mutation will receive the drug every two weeks&#8230; Another 100 mutation carriers will receive a placebo. And because many people do not want to know if they have &hellip; <a href=\"http:\/\/www.kateva.org\/sh\/?p=1266\">Continue reading <span class=\"meta-nav\">&rarr;<\/span><\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[3],"tags":[6,35],"class_list":["post-1266","post","type-post","status-publish","format-standard","hentry","category-share","tag-b","tag-s"],"_links":{"self":[{"href":"http:\/\/www.kateva.org\/sh\/index.php?rest_route=\/wp\/v2\/posts\/1266","targetHints":{"allow":["GET"]}}],"collection":[{"href":"http:\/\/www.kateva.org\/sh\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"http:\/\/www.kateva.org\/sh\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"http:\/\/www.kateva.org\/sh\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"http:\/\/www.kateva.org\/sh\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=1266"}],"version-history":[{"count":1,"href":"http:\/\/www.kateva.org\/sh\/index.php?rest_route=\/wp\/v2\/posts\/1266\/revisions"}],"predecessor-version":[{"id":1267,"href":"http:\/\/www.kateva.org\/sh\/index.php?rest_route=\/wp\/v2\/posts\/1266\/revisions\/1267"}],"wp:attachment":[{"href":"http:\/\/www.kateva.org\/sh\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=1266"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"http:\/\/www.kateva.org\/sh\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=1266"},{"taxonomy":"post_tag","embeddable":true,"href":"http:\/\/www.kateva.org\/sh\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=1266"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}