Inflammatory Bowel Disease: “tweaking ETS2 to be more active could make macrophages in the lab resemble the ones seen in IBD patients.” 🆓

Link. “when they looked at the genetic make-up of IBD patients, they found that 95% of patients in their sample carried at least one copy of a specific enhancer variant that seems to boost ETS2 activity…

… MEK inhibitors, should be able to quiet down the inflammation triggered by ETS2”

If it holds up … it’s big.

Incompetent Israeli gov influence operation on Twitter: “ChatGPT, the artificial intelligence-powered chatbot, was used to generate many of the posts”

Link. “FakeReporter, an Israeli misinformation watchdog, identified the effort in March …

… accounts with profile photos of Black men posted about being a “middle-aged Jewish woman.” …

… On its LinkedIn page, Stoic has promoted its ability to run campaigns backed by A.I … [later removed]”

Targeted specific NY legislators. I wonder how good the posts were.

Trump’s Apprentice con: “I signed an expansive nondisclosure agreement that promised a fine of $5 million and even jail time if I were to ever divulge what actually happened. It expired this year.”

Link. I signed an expansive nondisclosure agreement that promised a fine of $5 million and even jail time if I were to ever divulge what actually happened. It expired this year.

“Although very few programs are out-and-out fake, there is deception at play in every single reality program”

“theory of elite overproduction says, basically, that the educated elites whose career expectations can’t be satisfied will respond by getting mad at wider society and fomenting unrest” 🆓

Link. Noah pivots from Twitter stupidity to his pet theory. I share it because I agree with the idea that we have a worldwide glut of cognitive talent — and it’s getting worse.

Likely related to too much money chasing too few opportunities.