Link. Sociopaths are good at taking power.

His fraud led to several failed drugs and caused great harm.

Link. Useful reference.

Link. Nausea main problem so far. No weight gain and maybe some anhedonia relief.

The NYT article is solid except where they use word “rare”. I assume that was a fearful editor. The disease is not rare and it is terrible.

I appreciated the summary of how our genomic studies produced nothing.

🆓 link

Link. Ethically the pager attack was a significant improvement on blowing up Hezbollah fighters who routinely use civilians as shields.

Legally it violates a major arms treaty Israel signed.

Link. The shattered fragments of GOP sanity are hoping Trump loses and preparing for 2028. I hope they win their war.

Link. 100 million is a tap on the little finger for them.

Link. I was a minor cybercrime fighter in 1990s Japan for the early Internet version of carding.

Link. There is a name for what happens when technology cycles get too tight to predict.

Link. I’d love to know what Trump’s white woman base thinks of his protection.

Link. We need the legal right to take their phones and computers for a month and suspend their cell coverage. Detention should be reserved for children who use guns in crimes. (Twin Cities has an infamous 12yo)

Link. We lost this battle preemptively. Back when states started lotteries.

Link. Quantum field theory slides into popular science.

Link. Aaronson was my “go to” skeptic of impending encryption doom. He always said it was far away. And now it’s maybe not.

Link.

Link. “journalists spent the better part of a decade protecting her, coddling her, encouraging her to write gossip and call it “news,”

Link. The children of Twin Cities Hmong immigrants are now well represented in our medical schools.

Link. Brazil shows the way.

“Musk had made confronting Justice Moraes one of his pet issues this year, at times posting repeatedly about the judge, insulting him, calling for his jailing and vowing to defy his orders”

Link. Some suggestion they decrease OA. If you are on the lipid fence might consider.

Link. We have many shared bike trails. I don’t ding and I don’t do “left”. I go off trail to pass at such a distance collision is impossible. Most don’t seem to notice me and I practice my singletrack skills.

Link. Down 10% nationally over a year, biggest drop ever. Naloxone helps. Users seem smarter about managing fentanyl; I wonder if the fentanyl demographic is getting older. Post-COVID effect? Impossible to know why…

Link. Vile and unsurprising.

Link. I did degrees in 78, 82, 86, 91, 94 and I’m doing a UMN class now. Undergrads now are way more keen, intense, and stressed.

I think students know we have too much worldwide talent for too little demand, that modern life is chaotic, technology is moving too fast, rural collapse is giving us Trump, and now AI is coming. Econ numbers miss this.

Link. She lives a few miles from me, so our local celebrity. Probably better known locally for her election guides.

Link. Lowe is not impressed. So dumb.

Link. These are horrible diseases and now there is hope.

Link. Raccoon stool increasingly contains a parasite that destroys human brains. Flamethrower need varies based local incidence.

Link. “My question compulsion is still there, but LLMs are saving everyone. I set up a linguistics “collection” in Perplexity with appropriate prompts; now I type my questions into my phone (allowed in class). I get the answer with Perplexity and spare my classmates.”

Link. Not at all language specific, much more general than that. Presumably including applications not yet public.

Link. Post processing and tagging at indexing to facilitate retrieval.

Link. Climate engineering better work.

Link. I might restart my ChatGPT subscription.

This is bad news of course. Again, too fast.

Link. I think you’d want to be on current OS. and you need an archive copy for when things go wrong. He likes the slow careful migration rather than export/import.

Note TOTP advice carefully.

Link. Fast, confident, prone to dumb mistakes, but omniscient.

LLM assisted coding seems to work best for LLM experts.

Link. Like your braindead banking app. This is the single best iOS 18 feature I have read of so far. I am doing this.

Link. Too fast.

Link. Bezos and Ellison are similar that way. It’s not personal. You are grass.

With Musk it’s personal.

Link. I doubt this will work quickly enough but the idea is nice.

Link. “… a country where people can be persecuted purely for their membership in an undesirable group. Some Americans do want that. If you want that, vote for Trump”

Like Elon Musk. Any means to an end where the end is power. Or, in the case of Musk, wealth and power.

Link. Israel has been preparing to go to war with Iran for a long time.

Link. So Dec 24 rather than April 25 for me

Link. “Comparing RNA-seq and proteomics profiles of the two aged groups (treatment and control) with the two younger cohorts showed that metformin treatment rolled things back from 4 to 6 years”. 3 years of metformin for middle-aged cynomolgous monkeys.

I didn’t believe this result when I first read it. China has immense science fraud problems and the effect seems much too big. Published in Cell, but not, fwiw, in Nature or Science. I still think it’s too big an effect but if true it’s kind of Nobel gimme.

Link. I like to wait until April for macOS updates. I always hit the bugs.

Link. European bats are much less effected and American bats are evolving resistant traits. In the meanwhile researchers have identified several effective mitigations.

Link. If you think of American gun culture as a component of a proto-religion it is easier to understand and perhaps manage.

Link. Similar to adolescent pruning of key neural networks. Suggests optimizing or locking-in some bonding behaviors that favor infant survival. (But may decrease maternal survival. )

“By the ninth week of gestation, 80 percent of 400 brain areas analyzed showed decreases in gray matter volume and cortical thickness that continued through pregnancy, with areas shrinking by 4 percent on average. Change was particularly pronounced in the default mode network, which is instrumental in perceiving other people’s feelings and perspectives.”

Link. COVID accelerated this science. We will know more within a year. (mRNA original use case was cancer, not COVID)

Link. Reminiscent of Xerox and the mouse. Great business school case.

Link. Nothing prepared me for the 20s as well as my childhood years wasted on 1970s science fiction.

“The group proposed that countries set up A.I. safety authorities to register the A.I. systems within their borders…

…All three are winners of the Turing Award”

Link. If we have learned anything in the past decade it is that many people are above the law.

Link. I enjoyed this overview.