Modeling startup revenue: subscription vs perpetual license

Link. Nice business discussion: “To make my model, I started with bookings for the perpetual company and hard coded $5M in the first year on a reasonable ramp.  Then I made a set of reasonable assumptions (for a hot startup) that drove the rest of the model:  100% license bookings growth, a 20% maintenance rate, a 90% maintenance renewal rate, a 50% rate of professional services organization (PSO) services bookings relative to license, and a bookings-to-revenue conversion rate of 85% for PSO in the subsequent quarter”

Every disease is unique – one disease, many unique genomes

Link. We have lots of mutations. Different mutations produce similar diseases. Superficially similar in some cases.

“Both groups attribute the abundance of rare variants to the explosion of human populations after the invention of agriculture some 10,000 years ago. Because the population expansion is so recent, in evolutionary terms, natural selection has not had time to eliminate the harmful mutations.”

Mladic and srebenica

Link. “Mladic’s command systematically captured and killed thousands of men and boys as the Muslim population of Srebrenica sought to flee through the surrounding woods to toward the town of Tuzla”