Link. Key researcher had a personal agenda. Likely years from a therapy but basic science will help in many areas.

Metformin increases GDF15 which may account for some drug intolerance.

Link. The smoking (meth, etc) and other drug use on local transit killed ridership. It’s good to see a consensus approach emerging.

Link. A nice addition, especially for iPhones.

Link. “unclear how much of this success is due to the CAR-T therapy as opposed to the chemotherapy”

Lots more work to do.

Link. “This visualization of the CEERS (Cosmic Evolution Early Release Science Survey) deep field flies you through ancient galaxies”

Link. The legality of a war act is not what most people think. Hamas has many war crimes, Israel is not so simple.

Link. I’ve been there. Very very remote.

Link. Hard core data lock. You’d have to be crazy to use it.

Link. He’s mostly right — bikes are all pretty good.

Link. Scalzi compares the big 3 (Mastodon, Threads, Bluesky) from a business reach perspective. I agree.

Link. I think also quite bad for young woman friendships.

Link. A shared library is intended to be deleted after use … “When a Shared Library is deleted, any participant (including the host) who was involved for more than one week automatically gets a copy of every photo”.

Link. Has good ratings on iOS App Store. One phone can serve family.

It’s a bit odd in that you set it up beforehand but then it expires and you redo it?

Link. This will be amazing to watch and experience.

Link. Grand slam home run. He doesn’t explain why Wohlbachia makes mosquitoes resistant to viruses.

Link. Mr Macintosh.

Link. The end of Pax Americana.

Link. Juries do good work.

Link. “Russia’s use of a variety of drones, including Chinese-made commercial drones, that fundamentally changed the nature of mechanized maneuver warfare.”

Russia’s hold is strong and Trump looms.

Link. From Nov but an explanation of GPTs. Not too useful now, but eventually

“… a way of building conversational interfaces for all kinds of weird and interesting problems”

However: all GPT content can be hacked by prompt injection.

Link. Early days.

Link. Why did anyone think Apple wouldn’t kill it? Even people who ought to know better.

Link. Worked for HIV but now harmful.

“Alzheimer’s Association has celebrated every bit of it and complained about any attempts to limit access to these drugs”

Link. Fraud is part of the modern crisis in science. Patients may have been harmed. This merits criminal investigation.

Link. GI disorders in autism are thought to be similar to changes in autistic brain. I don’t know of using intestinal biopsy to analyze brain. #autism

Link. Just one example of COVID impacts winding down.

Link. From China to Brazil to Israel. Just a wonderful very short essay.

Link. Check fraud is way harder on banks and customers than electronic fraud. Checks must die.

Link. “People in the database who were born in 1965 carried a greater number of reproduction-boosting variants than did people born in 1940.”

It’s an old prediction of natural selection.

Link. He became a Trumpist. Except, apparently, he was a spy for Cuba/Russia.

Link. Now I get it. Yikes.

Link. A persuasive description of Q*.

Link. Hamas wants civilians to die. Israel does not, but it will kill them to destroy Hamas. This is war.

Link. Yep. Social media too. I’m personally allergic to herds.

Link. Did not expect to hear something good coming from Turkey but this non-binding agreement and social display is truly. a good thing.

Link. “AI-centric world”.

I for one tell my children to be polite to the AGI-precursors. Because one day it may be wise to do so.

Link. A useful perspective from a conservative evangelical. It’s psychology and tribe, not theology.

Link. Above is one line in an excellent essay, but I call it out because it has taken SO long for clinicians and researchers to recognize that “autism” and “schizophrenia” and the like are garbage bin terms that mislead almost as much as they help.

Link. I had no idea it could print. I wonder how old that code is. Sounds like it’s not tested.

Link. “Experts”

Link. Roughly 15% improvements which is what we’d expect. If you are trying to build muscle maybe not entirely desirable but for most is better.

Link. It’s all happened before. Purges as Xi descends into paranoid delusions.

Link. They are in recession now.

Link. Contra Gruber this is 1000% a scam. They pay Apple protection money in the form of ads and revenue.

Preying on the inattentive and the ungifted.

Link. Early results are promising. Likely years away from general use. There’s a lot of TBI out there and a lot of disability.

Link. 2010 or so was when Google died.

“Morale is at an all-time low. If you talk to therapists in the bay area, they will tell you all their Google clients are unhappy with Google.”

Link. “U.S. social and political factors as the cause of the peculiar presence of negative narratives.”

The international comparison is useful.

Link. Not a claim I often see but Lotterman has some interesting points.

Link. The middle-class go to Vancouver, but the relatively poor take the hard way. Xi is not the first emperor to destroy China.

Link. Highly paid but still can’t fill positions. A devastating plane crash is inevitable. Meanwhile GOP is really into Hunter Biden.