https://www.nejm.org/doi/full/10.1056/NEJMoa2502760?query=TOC
“The 5-year disease-free survival was 80.3% in the exercise group and 73.9% in the health-education group”
This is a much bigger effect than I would have expected. It’s a strong study design. There was no diff in body weight, this was not an obesity effect.