“CAR-T therapies have since entered phase I and II clinical trials for autoimmune conditions including systemic sclerosis, myositis and rheumatoid arthritis. Phase III trials are also under way for lupus and myasthenia gravis”

https://www.nature.com/articles/d41586-025-03885-w

“people in CAR-T-cell therapy trials for rheumatoid arthritis and lupus seem to be ‘cured’.”

Reasons for optimism. Major progress in last 2-3y.